Eupatorium Perfoliatum eup-per.

BONES. Stomach. Liver. Occiput. Bronchiæ. Muscles: Chest. Back. Limbs.

COLD AIR. Motion. PERIODICALLY: 7-9 A.M. 3rd. or 7th. day. Lying on part. Coughing. Smell or sight of food.

Vomiting bile. Sweating. Lying on face.

VIOLENT, ACHING, BONE-BREAKING PAINS (Coccl. Pyro. Rut.). Bruised, sore ache, < back. Restless, chilly and nauseated. Colds. Grippe; and catarrhal sequelæ. Bilious effects; yellow eyes, face, vomit, etc. Weakness.

Vertigo; sways to left; < lying on r. side; > vomiting. Sore throbbing head pains, < occiput; alternating with gouty pains. Sensation as of a metal cap on head. Migraine. Vomits bile at height of head pains, then >. Sore, aching eye-balls. Sneezing. Thirst, but drinks excite bitter vomiting or chill. Whitish stools. Urine now profuse, now scanty. Hoarse in A.M. Painful cough, from a laryngeal tickle; it hurts head; must hold chest. Raw, hot, sore chest and bronchi. Intense backache; as if beaten; ascending. Aching lower limbs. Bruised pain in calves. Dropsy of legs. Painful, gouty nodes. Thirst or nausea, then violent shaking chill; begins in small of back. Bitter vomiting, after chill or during heat. Burning heat. Scanty sweat. Malaria. Catarrhal fevers.

Complementary: Nat-m. Sep. Related: Bry. Nux-v.

Adapted to diseases of old people; worn-out constitutions, especially from inebriety; cachexia, from prolonged or frequent attacks of bilious or intermittent fevers. Bruised feeling, as if broken, all over the body (Arn., Bellis, Pyr.). Bone pains affecting back, head, chest, limbs, especially the wrists, as if dislocated. The more general and severe, the better adapted (compare, Bry., Mer.). Painful soreness of eyeballs; coryza, aching in every bone; great prostration in epidemic influenza (Lac. c.). Pains come quickly and go quickly and go away quickly (Bell., Mag. p., Eup. pur.). Vertigo; sensation as if falling to the left (cannot turn the head to the left for fear of alling, Col.). Cough: chronic; loose with hectic; chest sore, must support it with hands (Bry., Nat. c.); < at night; following measles or suppressed intermittents. Fever: chill to 9 a. m. one day, at noon the next day; bitter vomiting at close of chill; drinking hastens chill and causes vomiting; bone pains, before and during chill. Insatiable thirst before and during chill and fever; knows chill is coming because he cannot drink enough.

Is followed well: by, Nat. m. and Sep. Compare: Chel., Pod., Lyc., in jaundiced conditions. Bryonia is the nearest analogue, having free sweat, but pains keep patient quiet; while Eup. has scanty sweat and pains make patient restless.

In chills and fever, when chill comes on in the morning, with great pain in the bones, as though the bones would break; long bones particularly; then comes thirst, then chill with thirst, and as chill subsides, comes copious vomiting of bile.

Intense soreness and aching in the limbs, as if bruised or beaten. With chill more shivering than degree of coldness warrants; thirst several hours before the chill, which continues during the chill and heat.

Thoroughwort

Known as "Bone-set", from the prompt manner in which it relieves pain in limbs and muscles that accompanies some forms of febrile disease, like malaria and influenza. Eupatorium acts principally upon the gastro-hepatic organs and bronchial mucous membrane. It is a boon in miasmatic districts, along rivers, marshes, etc, and in all conditions where there is a great deal of bone-pain. Cachexia from old chronic, bilious intermittents. Worn-out constitutions from inebriety. Sluggishness of all organs and functions. Bone-pains, general and severe. Soreness. Marked periodicity (Ars; China; Cedron).

Throbbing pain. Pressure as if a cap of lead pressed over the whole skull. Vertigo; sensation of falling to left. Vomiting of bile. Top and back of head with pain and soreness of eyeballs. Periodical headache, every third and seventh day. Occipital pain after lying down, with sense of weight.

Cracks in corners of mouth, yellow coated tongue, thirst.

Tongue yellow. Taste bitter. Hepatic region sore. Great thirst. Vomiting and purging of bile, of green liquid several quarts at a time. Vomiting preceded by thirst. Hiccough (Sulph ac; Hydrocy ac). Avoids tight clothing.

Frequent, green watery. Cramps. Constipated, with sore liver.

Coryza, with sneezing. Hoarseness and cough, with soreness in chest; must support it. Influenza, with great soreness of muscles and bones. Chronic loose cough, chest sore; worse at night. Cough relieved by getting on hands and knees.

Perspiration relieves all symptoms except headache. Chill between 7 and 9 am, preceded by thirst with great soreness and aching of bones. Nausea, vomiting of bile at close of chill or hot stage; throbbing headache. Knows chill is coming on because he cannot drink enough.

Aching pain in back. Aching in bones of extremities with soreness of flesh. Aching in arms and wrists. Swelling of left great toe. Gouty soreness and inflamed nodosities of joints, associated with headache. Dropsical swelling.

Worse, periodically. Better, by conversation, by getting on hands and knees.

Compare: Bryon; Sepia; Natr mur; Chelidon. Nyctanthes arbor-tristis (bilious fever; insatiable thirst; bitter vomiting at close of chill; also constipation of children).

Tincture, to third attenuation.

Painful soreness of eyeballs; coryza; aching in every bone; prostration in epidemic of influenza (La Grippe).

Deep hard achings as if in the bones, with sore, bruised feeling all over, back, arms, wrists, legs.

Vomiting of bile between chill and heat. Chill 7 to 9 A. M.

Hoarseness in the morning, with soreness in chest when coughing; holds it with his hands.

When writing upon Arnica, I there compared several remedies which have a sensation as if bruised. This remedy might also have been mentioned there, as it has "Bruised feeling as if broken, all over the body." (Arnica, Bellis, Pyrogen.) The bruised feeling of Eupatorium is accompanied with a deep hard aching, as if in the bones.

Let us quote some of the symptoms illustrating: "Intense aching in the limbs and back as if the bones were broken." "Aching in the bones of the extremities, with soreness of the flesh; soreness of the bones." "Soreness and aching of the arms and forearms; painful soreness in both wrists as if broken or dislocated." "Soreness and aching of lower limbs; stiffness and general soreness when rising to walk." "Calves of the legs feel as if they had been beaten." "Aching pains as if in the bones, with moaning." These symptoms are all characteristic and may be found in influenza, bilious or intermittent fever, bronchitis, especially of the aged, and many other diseases. This is what gave the popular name "bone-set" to Eupatorium, because on account of the severe aching, as if the bones were broken, that occurred in an epidemic of intermittent fever this was the remedy that cured, or "set the bones." The epidemic was called break-bone fever. Of course this curative property of the drug was then discovered by accident, but abundant proving and verification have demonstrated the homœopathicity of such cures. So with Apis in dropsies. If this remedy has no curative properties other than it has for intermittent it would still remain a priceless boon to Homœopathy. It cures a kind of intermittent for which the great anti-periodic (Quinine) of the old school can do little or nothing. Three characteristics stand out prominently, to indicate the cases in which it is appropriate:

1st. As to time of chill -7 to 9 A. M.

2d. The intense aching in the bones before the chill.

3d. Vomiting of bile between chill and heat.

There are, of course, other symptoms which may appear in a Eupatorium case, but these three are a sure guide, and many authentic cures corroborate the genuineness. This remedy is also very useful in diseases of the respiratory organs. In the so-called la grippe of recent years it has proven in my hands very valuable; the "aching all over as if in the bones" being the leading symptom.

It also has hoarseness in the morning, like Causticum but while Causticum has more burning and rawness Eupatorium has more soreness in the chest; Ranunculus bulb. has pain in the chest when walking, turning, from touch or weather changing; when coughing has to support the chest with the hands, it hurts so (Bryonia, Drosera, Kreosot., Natrum sul., Sepia). Both remedies have aching in the bones especially in influenza or la grippe, but Eupatorium the most. If either of these remedies fails to cure the hoarseness, Sulphur will often complement them. Altogether, Eupatorium is to be remembered in many diseases having these characteristic symptoms. Eupatorium is especially adapted to worn out constitutions of old people or inebriates. Bryonia is near analogue, having free sweat, but pains keep patient quiet, while Eupatorium has scanty sweat, but pains make the patient restless.

Headache and nausea every other morning, when awaking. Soreness and pulsation on the back part of the head. Heat on the top of the head.

Great aversion to light.

Redness of the face, with dry skin.

Paleness ; of the mucous membrane of the mouth. Tongue covered with white fur. Soreness of the corners ; of the mouth.

Vomiting immediately after drinking, and preceded by thirst. Vomiting of bile, with trembling and great nausea, causing great prostration. Tight clothing is oppressive. Soreness in the region of the liver.

Constipation, with catarrh. Morning diarrhœa.

Dark-brown, scanty urine, depositing a whitish, clay-like sediment. Itching of the mons veneris.

Hectic cough, from suppressed intermittent fever. Cough, with flushed face and tearful eyes. Difficulty of breathing, attended with perspiration, anxious countenance, sleeplessness. Inability to lie on the left side.

Upper. Heat in the hands, sometimes with perspiration. Lower. Dropsical swelling of both feet and ankles. Heat in the soles of the feet, in the morning.

The intermittent fever paroxysm generally commences in the morning. Thirst a long time before the chill, which continues during the chill and heat. At the conclusion of the chill, vomiting of bile, or every draught. Pain in the bones (as if broken) all over, before the commencement of the chill. Headache, backache and thirst during the chill. Chilliness, with excessive trembling and nausea. Aching pains, with moaning during the cold stage. During the chill and heat, throbbing headache. The chill is induced or hastened by taking a drink of cold water. Great weakness and prostration during the fever. Headache and trembling during the heat. Vomiting of bile at the close of the hot stage. The fever goes off by perspiration and sleep. Coldness during nocturnal perspiration. Distressing pain in the scrobiculus cordis, throughout the chill and heat. During the apyrexia, loose cough.

Eupatorium perfoliatum. Boneset. Thoroughwort. N. O. Compositæ. Tincture of whole plant.

Anus, herpes of. Back, pain in. Bilious fever. Bones, pains in . Cough. Dengue . Diarrhœa. Fractures. Gout. Hiccough. Hoarseness. Indigestion. Influenza. Intermittent fever . Jaundice. Liver, soreness of. Measles. Mouth, cracks of. Ophthalmia. Relapsing fever . Remittent fever. Rheumatism. Ringworm. Spotted fever. Syphilitic pains. Thirst. Wounds.

Eupat. perfol . is an old-world remedy, having been recommended by Dioscorides for ill-conditioned ulcers, dysentery, stings of reptiles, chronic fevers, obstructed liver. The leading characteristic for its homœopathic use is the distressing bone-pains it causes, such as are found in connection with malarial fevers and influenza. Soreness will be found running throughout the proving: headache with soreness internally, parietal protuberances sore; with pain and soreness in eyeballs; cough with extreme soreness down trachea, soreness of chest, aching in limbs throughout the body. A characteristic cough of Eup. perf . has > by getting on hands and knees. W. P. Defriez reports a case in point: Every winter for several years the patient had been annoyed by a dry, hacking cough, with paroxysms lasting some time, only relieved by getting on hands and knees. Eupat. Perfol . cured. The chills of Eu. perf . begin in the small of the back, with aching in the limbs as though every bone in the body were being broken; high fever with increased aching, followed by sweat scanty or profuse; sweat > all pains except headache, which is < . Periodicity is marked. There may be a double periodicity: Chill morning one day, evening the next. The liver is strongly affected by Eup. perfol .; bilious vomiting and diarrhœa; bilious sick-headaches; cough arising from irritation of liver. Catarrhal symptoms are prominent. Nocturnal loose cough. Hoarseness with aching soreness of trachea. Hoarse, rough cough with scraping in bronchia. Cough with soreness, compelling the patient to hold his chest with his hands. Stiffness and general soreness. Cannot twist body either while standing, sitting, or lying. Cannot lie in bed on account of a feeling as if every bone was bruised, causing despair, moaning, and crying out. Bone-pains of all descriptions appear under Eupat. perf . Sleepiness and yawning. Sensation as if falling to left. Pain and extreme tenderness of left glutei muscles. Hale describes the fever of E. perfol . as follows: "The chill is nearly always in the morning , and is preceded for several hours by thirst , soreness and aching of the bones. The thirst continues during the chill and heat. The chill is attended by nausea, vomiting of bile, intense aching and soreness in the flesh of the extremities, and often all over the body. These symptoms continue during the heat, especially the vomiting, which is often painful and incessant. The heat is apt to be prolonged until evening or into the night, and may be followed or not by sweat (with chilliness). If no sweating occurs the apyrexia is short and attended by chilliness, nausea, thirst, and debility, showing that the febrile action never altogether subsides, giving a true type of Remittent fever — a fever in which Boneset is often our best remedy, especially if occurring in summer and autumn, and is attended by very severe bilious symptoms." Lying on back < cough. Kneeling with face towards pillow > cough. Rising up > headache. Eating = violent distressing pains which are only relieved by vomiting. There is intense thirst, but drinking cold water = shuddering and vomiting of bile. Chilliness predominates, wants to be covered; > in house, < in open air; < after being in ice-house. I have found Eup. perf . most useful in influenza.

Bryonia is the closest analogue; but Bryonia has free sweat, and the pains make the patient keep still. Eup. perfol. — has scanty sweat, and its pains cause restlessness. Compare also: Arn., Caps., Chel., Symph., Podoph., and Lycop.; nausea from smell of food, Colch. Compatible: Nat. mur. and Sepia, which also follow well.

Feels at night as if going out of his mind. — Moaning; anxiety; despondency. — Very restless; cannot keep still, though wishes to.

Early in morning whirling around in brain as if he had been whirled in cool screen: repeated after a short cessation. — Headache with a sensation of soreness internally; > in the house; < when first going into the open air; > by conversation. — Headache and nausea every other morning, when awaking. — Pain in occiput after lying, with sense of weight; must aid with hand in lifting head. — Beating pain in forehead and occiput, after rising. — Soreness and pulsation on the back part of the head. — Heat on the top of the head. — Violent headache, comes on before the chill rid lasts through all the stages, and is worst during the sweat.

Painful soreness of eyeballs. — Great aversion to light. — Painful soreness of lids.

Coryza, with sneezing; aching in every bone.

Paleness of the mucous membrane of the mouth. — Tongue covered with white fur. — Soreness of the corners of the mouth.

Nausea from smell of food or cooking. — Indigestion from alcohol, of old people. — Thirst for cold water. — Thirst for large draughts of cold water before and during chill. — Vomiting immediately after drinking, and preceded by thirst. — Nausea and vomiting of food. — Vomiting after every draught. — Vomiting of bile, with trembling and great nausea, causing great prostration. — Tight clothing is oppressive.

Soreness in region of liver; on moving or coughing. — Colicky pains in upper abdomen, with headache and other pains. — Abdomen full and tympanitic.

Constipation, with catarrh. — Morning diarrhœa. — Purging stools, with smarting and heat in anus.

Dark-coloured, clear urine. — Dark-brown, scanty urine, depositing a whitish, clay-like sediment. — Itching of the mons veneris.

Hoarseness. — Hoarseness < mornings; soreness in trachea and bronchia. — Cough with soreness and heat in bronchia; flushed face, and tearful eyes. — Hacking cough in the evening. — Cough from a cold, < 2 to 4 am.; excited by tickling in chest, causing tightness of chest; cough < lying on back, > kneeling with face towards pillow; scanty expectoration; painful fulness in head on coughing or blowing nose; lowness of spirits. — Hectic cough, from suppressed intermittent fever. — Difficulty of breathing, attended with perspiration, anxious countenance, sleeplessness. — Soreness in chest; < from inspiration. — Inability to lie on the l. side. — Sharp pain through r. chest on deep inspiration; feels at night as if going out of his mind; disturbed breathing frightens him.

Pressure as if heart was in too small a space. — Pain, soreness, and heaviness behind sternum and in cardiac region; < by least motion or turning body around.

Beating pain in nape and occiput; better after rising. — Aching pain in the back, as from a bruise. — Weakness in small of back. — Trembling in back during fever.

Aching in bones with soreness of the flesh. — Intense soreness and aching in limbs, as if bruised or beaten. — Wrists pain as if broken or dislocated. — Heat in the hands, sometimes with perspiration. — Dropsical swelling of both feet and ankles. — Heat in the soles of the feet, in the morning.

Jaundice.

Stretching and yawning; yawning before chill; sleepiness with difficult breathing. — Has to lie with head high. — Headache on awaking.

Thirst a long time before the chill, which continues during the chill and heat. — At the conclusion of the chill, vomiting of bile, or after every draught. — Pain in the bones (as if broken) all over, before the commencement of the chill. — Headache, backache, and thirst during the chill. — During the chill and heat, throbbing headache. — The chill is induced or hastened by taking a drink of cold water. — Distressing pain in the scrobiculus cordis, throughout the chill and heat. — Aching pains, with moaning during the cold stage. — Coldness during nocturnal perspiration. — Chilliness throughout the night and morning; trembling and nausea from least motion; intense aching and soreness in back and limbs; more shivering than the degree of coldness warrants. — The intermittent fever paroxysm generally commences in the morning. — Fever commences in morning; attended with painfulness, trembling, weakness, and soreness; but little or no perspiration. — Great weakness and prostration during the fever. — Headache and trembling during the heat. — Vomiting of bile at the close of the hot stage. — Vomiting of bile after the chill. — The fever goes off by perspiration and sleep. During the apyrexia, loose cough. — When there is perspiration it relieves all the symptoms except the headache.

Feels at night as if he was going out of his mind.
Moaning : with the aching pain ; during cold stage.
Anxious countenance.
Despondency, with fever.
Anxiety, despair, depression.
Headache > by conversation.

Faintness from motion, during fever.
Early in morning an attack of whirling around in brain, or, as he described it, "as if he had been placed in a coal screen and whirled around two or three times, repeated after a short cessation".
Sensation as if falling to the left.
Vertigo on attempting to rise in bed.

Aching in forehead.
Throbbing headache, pain extending from forehead to occiput, < left side.
Beating pain in forehead and occiput, > after rising.
Darting pains through temples, with sensation of blood rushing across head.
Shooting from left to right side of head.
Thumping in side of head above right ear.
Painful soreness in right parietal protuberance.
Heat on top of head, with pain, > by pressure.
Distress on top and in back part of head.
Soreness and pulsation in back part of head.
Intense pain in occiput ; distress.
Beating pain in nape and occiput ; > after rising.
Pain in occiput after lying, with sense of weight, must aid with hand in lifting head.
Headache, with sensation of soreness internally, > in the house, < when first going into open air, > by conversation.
Violent pain in head and back before chill or during chill.
Throbbing headache during chill and heat.
Headache and trembling during hot stage. θ Intermittent.
Headache and nausea every other morning, when awaking.
Nervous headache ; hemicrania.
Sick headache : when first awaking, continuing all day ; every other morning.
Suitable to bilious headache ; also headaches of persons suffering from ague.
Headache arising from disordered stomach.

Heat on top of head, with buzzing in ears.
Right parietal protuberance sore.
Insupportable heaviness in head.
Head drawn spasmodically backwards. θ Spotted fever.
Tinea capitis.

Great aversion to light.
(In sick :) Dimness over eyes when looking at small things ; could not sew for a whole week, all being dark.
Intense pain darting through eyes, as from needles ; eyes not inflamed.
Painful soreness of eyeballs.
Eyes glistened.
Sclerotica yellowish red.
Increased lachrymation, with cough.
Redness of margins of lids, with glutinous secretion from Meibomean glands.
Lachrymation and photophobia, left eye worse. θ Conjunctivitis.

Buzzing in ears ; heat on top of head.
Could hear everything while seemingly in profound sleep, but could not speak.

The smell of food, odors and cooking produced qualmishness.
(In sick :) Nose very dry and stopped up.
Fluent coryza ; sneezing ; hoarseness.
Coryza, with aching in every bone.
Catarrh, with sore fauces ; with costiveness.
Influenza : with weakness of pulse and great prostration ; with pain in bones ; with pain in back and limbs ; lassitude ; skin bathed in perspiration ; surface pale and morbidly sensitive ; of old people and
inebriates.
Epidemic influenza.

Anxious countenance with difficulty of breathing.
Sickly, sallow countenance.
Pale and stretchy.
Face : pale, sunken ; cholera like.
Cough, with flushed face and painful eyes.
Flushed face : with dry, hot skin ; during the fever ; with cough ; flushes of heat.
Redness of cheeks, with dry skin.
Face of a dull red color.
During heat face is of a dull mahogany-red color, and eyes glisten ; sclerotica yellow.
Sudden severe contraction of muscles of right cheek.

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Every time I take up one of these old domestic remedies I am astonished at the extended discoveries of medical properties in the household as seen in their domestic use.

All through the Eastern States, in the rural districts, among the first old -settlers, Boneset-tea was a medicine for colds. For every cold in the head, or running of the nose, every bone-ache or high fever, or headache from cold, the good old housewife had her Boneset-tea ready. Sure enough it did such things, and the provings sustain its use. The proving shows that Boneset produces upon healthy people symptoms like the colds the old farmers used to suffer from.

The common winter colds through the Eastern States and the North are attended with much sneezing and coryza, pain in the head, as if it would burst, which is aggravated from motion, chilliness with the desire to be warmly covered; the bones ache as if they would break; there is fever, thirst, and a general aggravation from motion. Such common everyday colds correspond sometimes to Eupatorium and sometimes to Bryonia. These two remedies are very similar, but the aching in the bones is marked in Eupatorium.

If this state goes on for a few days the patient will become yellow, the cold will settle in the chest, a pneumonia may develop, or an inflammation of the liver, or an attack commonly called a bilious fever. Such fevers frequently call for Bryonia and Eupatorium, each fitting its own cases.

These remedies are especially useful throughout New England, New York, Ohio, the North and Canada. They do not have this kind of a cold very frequently in the warmer climates, but Eupatorium is often indicated in the warmer climates for fevers, yellow fever, bilious fever, break-bone fever and intermittent fever. It seems to be useful in one kind of complaints in one climate and in another kind of complaints in another climate.

In the Southwest and the West, in the valleys of the great river Eupatorium. cures complaints beginning as if the back would break, great shivering from head to foot spreading from the back, great sensitiveness to cold, congestive headaches, flushed face, yellow ski and yellow eyes, pain in the abdomen, and in the region of the live inability to retain any food, nausea from the sight and smell of food the bones ache as if they would break, the fever runs high, the un is of a mahogany color, the tongue is heavily coated yellow, and the is nausea and vomiting of bile.

That gives the picture of Eupatorium in the Mississippi Valley, in the Ohio Valley, in Florida and Alabama and all through the Southern States. The most prominent symptom are the vomiting of bile, the aching of the bones as if they would break, the pains in the stomach after eating, and the nausea from th thought and smell of food.

The stomach is very irritable; the thought of food gags him. The patient desires to keep still, but the pain is s severe that he must move and so he appears restless. These are among the acute manifestations, and are things only very general th we must take up and apply to sick people.

Continue in Kent 36 more passages →

Adapted to diseases of old people; worn-out constitutions, especially from inebriety; cachexia, from prolonged or frequent attacks of bilious or intermittent fevers.

Bruised feeling, as if broken, all over the body (Arn., Lac can., Pyr.).

Bone pains; affecting the back, limbs, head, chest, particularly the wrists as if dislocated, the eyeballs; the more general and severe the better adapted. Like Bryonia, they are accompanied by headache, constipation and pain in hepatic region, but here the similitude ends.

In Bryonia, the perspiration is profuse, easily excited by motion, and the pains compel patient to lie still upon the painful side.

In Eupatorium the sweat is scanty or wanting, the pains cause restlessness without any relief from motion, and there is entire inability to lie on left side.

Pains as if broken; come quickly and go away as quickly (Bell., Mag. p., Eup. pur.—reverse of Stan.).

Vertigo: sensation as if falling to the left (cannot turn the head to the left for fear of falling, Col., Con.).

Cough: chronic; loose with hectic; chest sore, must support it with hands (Bry., Nat. c.); $<$ at night; following measles or suppressed intermittents.

Painful soreness of eyeballs; coryza, aching in every bone; great prostration in epidemic influenza (Lac c.).

Followed well by Natr. mur., Sepia and Tub.

Motion; drinking; uncovering.

Tertian; double tertian; rarely double quartan, and then only when changed from original type by Quinine. All types may be cured by it. Anticipating, remittent, bilious, malarial; sporadic La Grippe.

Quotidian; tertian; quartan; double tertian and quartan. Anticipating. Every fourteen days. Irregular both in type and stage.

Tertian; double tertian, rarely double quartan. Anticipating. All types may be cured with Eupatorium.

7 A. M.; 7 to 9 P. M.; 7 to 9 A. M. one day, lighter chill at 12 M. next day; 10 A. M.; 12 to 2 P. M.; 5 P. M. Will cure without reference to time, when totality of symptoms are present.

Characteristic; 1 to 2 P. M., 12 to 2 A. M. Afternoon paroxysm predominates.

7 A. M. or 7 to 9 A. M.; 7 to 9 A. M. one day, lighter chill at 12 M. next day. Forenoon predominates.

Insatiable thirst, but drinking causes nausea and vomiting, and hastens the chill. Sick stomach and thirst night before the paroxysm. Thirst, sometimes for warm drinks (Casc., Ced ), one to three hours before the chill; he knows the chill is coming because "he cannot drink enough" (knows chill is coming because she is thirsty, Caps., Cinch., Nat.); yawning, stretching, pain in back, especially over right ilium, and the bones of extremities as if broken. Colicky pain in the upper abdomen (Coc.); painful soreness of the eyeballs. Must be covered, before and during chill (covered during entire paroxysm, Nux). Hungry (Cina).

No thirst. Headache, with vertigo and pale face; pain in bowels and watery diarrhœa. Debility; great weariness; must lie down. Malaise.

Eupatorium.

Insatiable thirst. Drinking hastens chill and causes vomiting. Know chill is coming because "he cannot drink enough." Yawning, stretching, backache, and bone pains in extremities.

Arsenicum.

With intense thirst; but drinking water increases the nausea, and causes bitter vomiting (drinking causes vomiting, Ars.—drinking increases the chill, Caps.). Chilliness with excessive trembling and nausea (from the least motion). Chilliness in the morning, heat throughout the whole day, but no perspiration. Chill may leave for a few minutes and return again, but no heat in the interval (reverse of Ars., which has alternate chill and heat). Shivering increased by motion; intense, throbbing headache; pain in back and bones of extremities; moaning with pain; distressing pain in stomach and spleen. Yawning and stretching; more shivering than the degree of coldness warrants.

Must be warmly covered (Nux). Begins in or may spread from the back, or runs up the back (begins in back between the should- ers, Caps., Polyp.—begins in lumbar region, Eup. purp.).

At close of chill, nausea and vomiting of bitter fluids and bile, aggravated by drinking, or after every draft vomiting (Caps. —sour vomiting at close of chill, Lyc.). Chilly one day, colic the next.

Irregular; mingling of chilliness and heat; or chills and heat alternate; ameliorated by external heat. Thirst is not always present; if present, drinks little and often, but generally for hot drinks. Thirst, except for hot drinks, contra-indicates.

With great thirst. Begins in back; with yawning, stretching, backache and bone pains. May leave and return, but no heat in interval. Must be covered warmly (Nux v.). Bitter vomiting at close of chill. More shivering than coldness warrants.

Preceded by thirst, which is often felt most between chill and heat (Ars., Cinch.), or there may be little thirst, when cephalalgia and bone pains are increased; trembling, faint from motion; great weakness; cannot raise the head while the fever lasts; cheeks mahogany red; throbbing headache; internal sore- ness from head to foot, all over the body (Arn.); sleep with moaning. Seldom any nausea during this stage, but bitter vomit- ing (sour vomiting, Lyc.) occurs at close of heat if absent at close of chill. Heat and lachrymation. Much shivering even during heat. "A swallow of water will make him shiver" (will make him shudder, Caps.). Pain in scrobiculus cordis. Fever in the forenoon, preceded by thirst early in the morning, but no chill; attended by fatiguing cough, and not followed by perspiration.

Intense, dry, burning, long-lasting heat, pungent to the touch, and insatiable thirst for cold water. Great restlessness. Must be uncovered. Heat as if hot water were coursing through the blood-vessels.

Great weakness; cannot raise the head while heat lasts. Rarely any thirst; cheeks mahogany red, and intense throbbing headache; a swallow of water produces shivering. Body sore from head to foot.

Generally scanty, or absent altogether, in which case the headache continues for several hours after fever is gone (Ars.).

When there is much perspiration, it brings relief of all pains ex- cept cephalalgia, which is increased (sweat relieves all pains,

Nat.). Coldness during nocturnal sweat. Perspiration; at night giving no relief; during sweat the slightest movement of patient, or jar of bed, will cause a transient chill to run through the frame, especially along the back on uncovering (Nux); not debilitating if profuse (reverse of Cinch. and Carbo v.). When chill is severe, sweat is light or wanting and vice versa.

With unquenchable thirst for large quantities of water, which causes vomiting. Cold, clammy. Great weakness and prostration. Previous symptoms relieved during sweat.

Scanty or absent. If much, is more profuse at night and then cold. Relieves all pains except cephalalgia, which is increased. When chill is severe, sweat is light or wanting, and vice versa.

Coated white or yellow. Taste, insipid, bitter; food has no taste (Dros.). Desire for ice cream; thirst. Pale- ness of mucous membrane of mouth (Fer.). Cracks at the com- missures of the lips (Nat.). Canine hunger after Quinine.

Ayprexia.—Imperfect; very little remission. Jaundiced hue of skin and conjunctiva; loose cough; if any sweat, it is attended with chilliness and worse from motion and uncovering. Bone pains are present in every stage, and only gradually disappear with disappearance of sweat. Feels worse morning of one day, and afternoon of next. The severity of vomiting has relation to time of eating; the nearer the meals the surer to vomit; first of ingesta, afterwards of bile, which is usually bitter.

"Eupatorium has been a favorite remedy with the most suc- cessful practitioners where remittent and intermittent fevers have prevailed epidemically in miasmatic districts, along rivers, at fisheries, on marshes, and their several neighborhoods."—C. J.

HEMPEL, S. C., I., p. 696.

"Eupatorium perf., both by its pathogenesis and clinical verifi- cation in practice, is one of the most valuable of the Materia

Medica in the treatment of western intermittents."—J. S. DOUG-

LAS.

To this statement I would add that its efficacy is not bounded by latitude. Sometimes it corresponds to the genus epidemicus, and will alone cure nearly every case, particularly if occurring in autumn. It vies with Arsenicum, Cinchona and Natrum mur. as one of our sheet anchors in this disease; its symptoms are "clear- cut" and well defined; its action prompt and decisive. It has cured in all potencies from the tincture to the cm.

Arsenicum.

Tip red, sides furred, with red streaks down middle; brown-blue. Desire for acids, brandy; water tastes bitter; aversion to food.

Coated white or yellow, pale; food tasteless, insipid, bitter. Desire for ice cream. Canine hunger after Quinine. Commissures of lips cracked (Nat.).

Never clear. Great weakness and prostration. Face pale, sallow, sunken or bloated. Debilitating, watery diarrhœa. General anæmic appearance.

Fevers contracted at sea-shore watering-places, appear in autumn, or "wintered over" and come on in spring.

Eupatorium.

Imperfect, very little remission. Jaundiced hue of skin and conjunctiva; loose cough. Bone pains in every stage, unless relieved by sweat.

Fevers of miasmatic, marshy regions; autumnal; often the genus epidemicus. Apt to become remittent.

Feels at night as if he was going out of his mind.
Moaning with the aching pain.
Anxious countenance.
Desponding, with fever.

Faintness from motion, during the fever.
Whirling around in the brain; early morning.
Sensation, as if falling to the left.

Headache with the chill.
Headache and nausea every other morning, when awaking.
Soreness and pulsation on the back part of the head.
Heat on top of the head; distressed feeling.
Throbbing headache during chill and heat.
Headache and trembling during the hot stage of the intermittent.
Shooting from left to right side of head.
Sick headache: when first awaking, continuing all day; every other morning.
Pain in occiput after lying, with sense of weight, must aid with hand in lifting head.

Right parietal protuberance sore.
Head drawn spasmodically backwards. θ Spotted fever.

Great aversion to light.
Painful soreness of eyeballs.
Redness of margins of lids, with glutinous secretion from meibomian glands.
Intense pain darting through the eyes, as from needles; eyes not inflamed.
Sclerotica yellowish.

Buzzing in ears, heat on top of heat.

Coryza, with aching in every bone.
Influenza, with weak pulse, prostration, bone sore; especially with inebriates and old people.

Sallow, sickly, with intermittent fever; pale with catarrhs; red, skin dry.
Sudden severe contraction of muscles of right cheek.

Tongue covered with white fur, or yellow-coated.
Taste bitter.

Paleness of the mucus membrane of the mouth.
Breath smells mouldy, sourish.

Fauces sore.

Longs for ice cream.
Distaste for food.
Canine hunger with or before argue, or after quinine.
Loss of appetite.
Thirst for cold water.

After drinking cold water: shuddering; vomiting bile.
After eating: violent distressing pains; no case until all is vomited.

Sick stomach, night before ague paroxysm.
Vomiting; as the chill passes off, or between chill and fever; of bile at the close of hot stage; of bile, with trembling and great nausea, causing great prostration; preceded by thirst.

Distressing pain in scrobiculum during chill and heat.

Soreness in region of the liver.
Tight clothing is oppressive.

Violent colicky pains in upper abdomen, with headache and other pains.
Abdomen full and tympanitic.

Considerable griping, worse after stool, with tenesmus.
Emission of fetid flatus, with relief.
Morning diarrhœa.
Frequent green, watery stools.
Constipation, with catarrh.

Dark brown, scanty, depositing, a whitish clay-like sediment; profuse, pale, with gout.
Inflammation of meatus urinarius, in a woman.

Itching of the mons veneris.

Hoarse; throat dry, sore; can hardly talk; work mornings, when he gets up.

Difficult of breathing, attended with perspiration, anxious countenance, sleepiness.
Great oppression of the chest; a full breath hurts; rattling on chest.
Dyspnœa with hard and shoulders high.
Must lie with head and shoulders high.

Hectic cough, from suppressed intermittent fever.
Loose cough during apyrexia; also at night, after measles.
Rough, scraping cough, chest sore; must support it with the hands; flushed face, tearful eyes.

Soreness in chest; worse from inspiration.
Pain and soreness behind the sternum; heart feels as if in too small a place.
Oppression in middle of sternum; feels as if something were pressing against his heart; palpitation.
Pain through right nipple, when breathing.
Deep-seated pain in left side and right shoulder.

Intense aching in back and limbs.
Pain in back of neck and between the shoulders.
Aching soreness in the back.

Stiffness of arms and fingers during chill.
Wrists pain as if broken or dislocated.
Heat in hands, sometimes with sweat.

Severe pains, like cramps, waken out of sleep; cold sweat follows.
Lameness in right hip and lower extremity when walking.
Flagging of muscles of left thigh, as if falling off the bone.
Burning of skin of inside of thighs.
Throbbing in right foot.
Stinging, as from pains in feet; beginning of chill.
Heat in soles of feet in the morning.
Pain in heel, as if stabbed.
Sharp, burning pain in feet, could not keep her shoes on.
Gouty swelling of left big toe; ankles and feet dropsical.

Intense aching in limbs, as if the bones were broken; back and limbs ache, as if broken.
Pains all over; left ankle, hip, shoulder; pains come instantly and go away as quickly.

Very restless, can's keep still, though there is a great desire to do so.
Not relieved by motion. Motion: 2, 40. Walking: 33. Lying: 3, 26. Cannot raise head: 40.

During fever, weak, faint, nervous, trembling.

Yawning and stretching, with intermittent.
Sleepy; difficulty breathing.
Profuse sleep at noon, yet can hear every sound.
Sleepless, with the fever.
On awaking, headache.

Morning: 2, 3, 20, 25, 33, 40. 7-9 A.M.: 40. Noon: 37, 40. Night: 27, 40. All day: 3.

Wants to be warmly covered during chill.
Uncovering: 40.

Before chill: thirst; cough the night before; pain above right ilium; yawning.
During chill: thirst, head throbs; aching all over, as if in the bones; more shivering than the degree of coldness warrants; trembling, nausea; moaning with pains.
At end of chill: vomiting bile.
Chill spreads from the back; begins between 7 and 9 A.M.
Chill early morn one day, light chill about noon next day.
Fever preceded by thirst, cannot raise the head; cheeks red; throbbing headache; sleep and moaning; trembling, faint from motion; vomiting of bile at end of hot stage, followed by slight sweat and sleep.
Skin bathed in sweat; or sweat scanty.
Nightly sweat, with chilliness, from moving or uncovering.
Hectic from suppressed ague.
Bilious fever; remittent fever.
Dengue.

Every other morning: Intermittents of any type, but especially the tertian.
Pain come quickly and go quickly: 34.

Inability to lie on left side.
Right: 4, 8, 28, 33, 40. Left: 2, 28, 33. Left to right: 3.

Sense of numbness, as if the flesh were falling from the bones.
Pains in back, head, etc., the more general and severe, the better adapted.

Must support with the hands: 27.

Eruptions develop tardily; especially measles.
Spotted fever; head drawn backwards; limbs ache, feel sore.
Ringworms.

Old people.
Inebriates.

Eup perf. is followed well by Sepia or Natr. mur.

A tincture of the fresh plant is used.

Bry., Ars.; and probably Carduus ben.

▶ Soreness in bones. ▶ Bruised feeling in every bones, preventing lying in bed and causing despair, moaning and crying out. ▶ Inability to lie on left side. ▶ Aggravation in the morning of one day and in the afternoon of the next. ▶ Headache, agg. first going into the open air, amel. the house and by conversation, with internal soreness. ▶ Whirling around in brain in morning, as if placed in a coal screen and whirled around two or three times, soon repeated. ▶ Pain in forehead, extending to occiput, agg. left side. ▶ Darting through temples, with sensation of blood rushing across head.

Periodical headaches, especially in occiput, throbbing, sensation of great soreness of eyeballs, soreness of scalp, etc.

Violent coryza or influenza, with thirst, heaviness over head, bone-pains, soreness of eyeballs, etc.

Inflammation of larynx, with soreness and hoarseness, soreness extending into the bronchi and trachea, usually with bone-pain and soreness of the chest generally. ▶ The cough is generally agg. lying on back, amel. lying on face; cough hurts the head and chest, the patient holds the chest with the hands (Dros.); generally there is no expectoration, or at least very little.

The characteristic fever, intermittent fever, for which this drug should be prescribed, has thirst beginning before the chill and continuing during both chill and heat; it is extremely important to observe that vomiting is particularly apt to result from drinking or taking any nourishment, either before or after the chill and fever; this vomiting from taking water is much more characteristic of the drug than the bone-pains, especially the vomiting of bite as the chill passes off; the violent bone-pains, the violent headache, pain and soreness of the muscles, are the universal accompaniments of the intermittent fever; the patient feels as if all the bones were breaking; it is very frequently observed that these Eupatorium cases present an incomplete paroxysm, for the chill and fever are well marked, and perhaps violent, and yet the sweat is entirely wanting; while this is usually the case, it is true that the drug cures cases in which there is a decided sweating stage. ▶ Valuable for catarrhal fevers, especially if there is bilious vomiting, with soreness of the chest and muscles and bone-pains, running from eyes and nose, soreness of the eyeballs, soreness of head, etc.

▶ Eyeballs sore (Bap.). ▶ Increased lachrymation. ▶ Redness of margins of lids, with glutinous secretion from Meibomian glands. ▶ Dim vision of looking at small things. ▶ Nose dry and stopped. ▶ Redness of face; of with dryness of skin.

▶ Tongue coated white (Bry.). ▶ Mucous membrane of mouth pale. ▶ Insipid taste. ▶ Throat dry.

Desire for ice-cream. ▶ Loss of appetite. ▶ Thirst for cold water (Bry.); T. for something cold at night. ▶ Belching of tasteless wind, with feeling of obstruction at pit of S. ▶ Nausea; from odors, the smell of cooking, etc. with vomiting, free perspiration and copious expectoration. ▶ Retching and vomiting of bile. ▶ Vomiting preceded by thirst (Ars.); V. after every draught (Ars.); of food. ▶ Feeling as if something ought to come up without ability to raise it. ▶ Fulness. ▶ S. seemed contracted from side to side. ▶ Heat. ▶ Beating in epigastrium at night.

Tight clothing is oppressive. ▶ Tightness in left hypochondrium. ▶ Soreness in liver region, with fulness.

Diarrhœa in morning. ▶ Purging, with smarting and heat in a anus. ▶ Four or five watery stools in a day. ▶ Loose scanty; stool, with tenesmus. ▶ Urine dark, clear. ▶ Scanty urine; and high-colored. ▶ Urine copious limpid.

▶ Cough, with soreness and heat in bronchi; C. agg. evening; hacking in evening.

Aching under left breast; behind sternum, with soreness, weight, inability to inspire naturally or twist the body to right or left because of the soreness, he feels best when lying on the back with his arms down and legs straight, but inability to move to right or left, inability to twist the body when standing, sitting or lying. ▶ Soreness on a full inspiration; S. from coughing, amel. going down on his knees. ▶ Grating sensation on very deep inspiration.

Pressure as if in too small a place.

Beating pain in nape; amel. rising, and in occiput. ▶ Bruised pain in back. ▶ Trembling in back during fever. ▶ Pain and soreness in small of B. as if beaten; deep-seated P. in loins, with soreness from touch. ▶ Weakness of small of B.

▶ Aching bones, with soreness of flesh. ▶ Soreness and aching in arms and forearms; above and below elbows, as if beaten. ▶ Painful soreness of wrists as if broken or dislocated. ▶ Stiffness of arms; of fingers, with obtuseness of touch; of lower limbs on rising to walk, with soreness. ▶ Soreness of lower limbs, with aching. ▶ Pain in right hip when sitting; P. in left gluteal muscles, passing round in front of trochanter major, with sensitiveness. ▶ Calves feel as if they had been beaten. ▶ Pricking in soles. ▶ Pain in upper part of left foot, with soreness and with increased sensitiveness of left great toe, the pain in foot agg. standing upon it. ▶ Pain in first joint of great toe, left then suddenly moving to right.

Intermittent, quotidian, tertian and quartan. ▶ The paroxysm usually begins in the morning, thirst several hours before the chill, continuing during chill and heat; C. in morning, heat through the day, but no sweat; C. through the night and in the morning, with nausea from the least motion; C., with nausea and trembling; C. alternating with flashes of heat. ▶ General shuddering proceeding from the stomach. ▶ Pungent heat at night, with sweat. ▶ Heat on vertex, with pain which is amel. by pressure; H. of soles in morning. ▶ Sweat at night, with chilliness from motion or uncovering.

General soreness and aching in the bones; cannot lie in bed; moans and cries.

Pain at first < going into the open air, with internal soreness.

Eyeballs sore.

Violent coryza, with bone pains, etc.

Extreme thirst.
Nausea, retching and vomiting of anything taken into the stomach; of bile.

Cough, with soreness and heat in the bronchi and soreness of the chest generally, with bone pains.
Cough < lying on the back, > lying on the face; cough hurts the head and chest so that he holds the chest with the hands.

Bruised pain in the back as if beaten.
Back feels weak.

Most violent aching in all the bones, with soreness of the flesh as if beaten.
The wrists feel broken or dislocated.
Soreness of the lower extremities, with aching.
Calves feel as if they had been beaten.

Clinical:
Chill, preceded by thirst, which continues during the fever.
Vomiting occurs before or after the chill and fever, caused by taking water or food into the stomach.
Violent bone pains; headache.
A bruised feeling of the chest always accompanied the paroxysms.
The paroxysm is generally incomplete; usually the sweating stage is suppressed.
Catarrhal fever, with bilious vomiting, or other symptoms.

Indicated in malarial conditions and fevers, chiefly intermittent fever; also in influenza. The severe aching in the (long) bones and the thirst are characteristic.

Chill. Always preceded by thirst; thirst gives warning of the approach of the chill; drinking will hasten it. At 7 to 9 a. m. one day, at noon the next day. Gaping, stretching, backache, aching in the (long) bones. At close of the chill, bitter vomiting, worse from drinking water.

Thirst during the chill and fever.

Fever, hot, with headache and thirst; to drink water makes him shiver.

Headache at top and back of head, with soreness of the eye-balls; periodical, at certain days (third or seventh).

Bilious condition; yellow tongue; bitter taste, soreness in liver; thirst; vomiting of bile; preceded by thirst; green, watery diarrhoea.

Hoarseness, with soreness in the chest; chronic cough, loose, worse at night.